A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system |
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Authors: | Pei-wen Pan Alejandra Rodriguez Seppo Parkkila |
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Affiliation: | (1) Institute of Medical Technology, University of Tampere and Tampere University Hospital, 33520 Tampere, Finland |
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Abstract: | Background Carbonic anhydrases (CAs) are physiologically important enzymes which participate in many gastrointestinal processes such as acid and bicarbonate secretion and metabolic pathways including gluconeogenesis and ureagenesis. The genomic data suggests that there are thirteen enzymatically active members of the mammalian CA isozyme family. In the present study, we systematically examined the mRNA expression levels of all known CA isozymes by quantitative real-time PCR in eight tissues of the digestive system of male and female mice. |
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