The ins and outs of peroxisomes: co-ordination of membrane transport and peroxisomal metabolism |
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Authors: | Rottensteiner Hanspeter Theodoulou Frederica L |
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Affiliation: | Medical Faculty of the Ruhr-University of Bochum, Department of Physiological Chemistry, Section of Systems Biochemistry, 44780 Bochum, Germany. Hanspeter.Rottensteiner@rub.de |
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Abstract: | Peroxisomes perform a range of metabolic functions which require the movement of substrates, co-substrates, cofactors and metabolites across the peroxisomal membrane. In this review, we discuss the evidence for and against specific transport systems involved in peroxisomal metabolism and how these operate to co-ordinate biochemical reactions within the peroxisome with those in other compartments of the cell. |
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