A new drug-release method using the Staudinger ligation |
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| Authors: | Azoulay Michel Tuffin Gérald Sallem Wafa Florent Jean-Claude |
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| Affiliation: | UMR 176 CNRS/Institut Curie, Centre de Recherche, 26 rue d'Ulm, F-75248 Paris Cedex 05, France. |
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| Abstract: | Many drugs induce severe side-effects caused by their lack of selectivity. One way to overcome this problem is to design a specific system which releases a free drug in a controlled manner. Herein we describe a new way to liberate a drug from a prodrug using the Staudinger ligation as the trigger. |
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