| 蓖麻根提取物对HepG2,NCI-H460和SGC-7901细胞增殖及凋亡作用的影响 |
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| 引用本文： | 唐祖年,韦京辰.蓖麻根提取物对HepG2,NCI-H460和SGC-7901细胞增殖及凋亡作用的影响[J].广西植物,2011,31(4):564-567. |
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| 作者姓名： | 唐祖年 韦京辰 |
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| 作者单位： | 桂林医学院药理教研室,广西桂林,541004 |
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| 基金项目： | 广西教育厅科研基金(200710MSI3)~~ |
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| 摘 要： | 探讨蓖麻根不同提取物对肝癌HepG2细胞株、肺癌NCI-H460细胞株和胃癌SGC-7901细胞株增殖及其凋亡的影响.采用MTT法检测蓖麻根不同提取物处理48h、72h对HepG2细胞、NCI-H460细胞和SGC-7901细胞增殖的抑制率；Hoechst 33258荧光染料染色法观察HepG2细胞凋亡,流式细胞术检测...
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| 关 键 词： | 蓖麻根提取物 MTT 肿瘤细胞株 细胞凋亡 |
Effects of Ricinus communis Root Extract on proliferation and Apoptosis of HepG2,NCI-H460 and SGC-7901 cell |
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| TANG Zu Nian,WEI Jing Chen.Effects of Ricinus communis Root Extract on proliferation and Apoptosis of HepG2,NCI-H460 and SGC-7901 cell[J].Guihaia,2011,31(4):564-567. |
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| Authors: | TANG Zu Nian WEI Jing Chen |
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| Institution: | TANG Zu-Nian,WEI Jing-Chen(Department of Pharmacology,Guilin Medical College,Guilin 541004,China) |
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| Abstract: | Effects of Ricinus communis root extracts on proliferation and apoptosis in human hepatoma cell lines HepG2,lung cancer cell lines NCI-H460 and gastric cancer cell lines SGC-7901 were investigated.Cell proliferation rate of different root extracts on HepG2 cells,NCI-H460 cells and SGC-7901 cells was determined by MTT assay.The apoptosis of HepG2 cells was observed by fluorescent dye staining with Hoechst 33258.HepG2 cell cycle was measured by flow cytometry.The results showed that petroleum ether extract of... |
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| Keywords: | Ricinus communis MTT tumor cell apoptosis |
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