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A psychophysiological marker of attention deficit/hyperactivity disorder (ADHD)--defining the EEG consistency index
Authors:Kovatchev B  Cox D  Hill R  Reeve R  Robeva R  Loboschefski T
Affiliation:Center for Behavioral Medicine Research, University of Virginia Health System, Box 800137, Charlottesville, Virginia 22908, USA. boris@virginia.edu
Abstract:This study continues our research to further validate the idea that ADHD (Attention Deficit/Hyperactivity Disorder) interferes with transition from one task to another and this interference can be quantified by a Consistency Index (CI) derived from a specific mathematical representation of EEG data. We reanalyze 32 previously reported data sets present new data for 35 boys and girls, ages 7-12, ADHD or control. Each data set contains EEG, recorded and digitized while participants perform consecutive 10-min tasks: video, reading, and math. For boys, the CI in ADHD was four times lower than in controls, p < .005, for girls this difference was two times, p < .05. ADHD/control classification based on the CI coincided with the DSM-IV criteria for 88% of the boys and for 67% of the girls. Post hoc analysis indicated that the classification utility of the CI diminished with age. A CI below 40% could be a discriminating, reliable, and reproducible marker of ADHD in young boys.
Keywords:attention-deficit/hyperactivity disorder (ADHD)  electroencephalography (EEG)  mathematical modeling
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