Three-dimensional convective alveolar flow induced by rhythmic breathing motion of the pulmonary acinus |
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Authors: | Sznitman Josué Heimsch Fabian Heimsch Thomas Rusch Daniel Rösgen Thomas |
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Institution: | Institute of Fluid Dynamics, ETH Zurich, CH-8092 Zurich, Switzerland. sznitman@ifd.mavt.ethz.ch |
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Abstract: | Low Reynolds number flows (Re<1) in the human pulmonary acinus are often difficult to assess due to the submillimeter dimensions and accessibility of the region. In the present computational study, we simulated three-dimensional alveolar flows in an alveolated duct at each generation of the pulmonary acinar tree using recent morphometric data. Rhythmic lung expansion and contraction motion was modeled using moving wall boundary conditions to simulate realistic sedentary tidal breathing. The resulting alveolar flow patterns are largely time independent and governed by the ratio of the alveolar to ductal flow rates, Qa/Qd. This ratio depends uniquely on geometrical configuration such that alveolar flow patterns may be entirely determined by the location of the alveoli along the acinar tree. Although flows within alveoli travel very slowly relative to those in acinar ducts, 0.021%
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