Sucutiniranes A and B, new cassane-type diterpenes from Bowdichia nitida |
| |
| Authors: | Matsuno Yosuke Deguchi Jun Hirasawa Yusuke Ohyama Kunio Toyoda Hiroo Hirobe Chieko Ekasari Wiwied Widyawaruyanti Aty Zaini Noor Cholies Morita Hiroshi |
| |
| Affiliation: | Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo 142-8501, Japan. |
| |
| Abstract: | Two new cassane-type diterpenes, sucutiniranes A (1) and B (2), have been isolated from the seeds of Bowdichia nitida together with 6alpha-acetoxyvouacapane (3) and 6alpha,7beta-diacetoxyvouacapane (4), and the structures of 1 and 2 were elucidated by using 2D NMR data and chemical correlations. Sucutinirane A (1) and 3 showed a moderate cytotoxicity against human colon carcinoma COLO201 cells, and 6alpha,7beta-diacetoxyvouacapane (4) showed in vitro antiplasmodial activity against parasite Plasmodium falciparum 3D7. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
