Purine composition of the crystalline cytoplasmic inclusions of Paramecium tetraurelia |
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| Authors: | Creutz Carl E Mohanty Sarina Defalco Tony Kretsinger Robert H |
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| Institution: | Department of Pharmacology, University of Virginia, Charlottesville 22908, USA. Creutz@virginia.edu |
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| Abstract: | Crystalline cytoplasmic inclusions were isolated by differential centrifugation from mass cultures of Paramecium tetraurelia feeding on Klebsiella pneumonia. Physical and chemical measurements of intact and solubilized crystals determined that they consist primarily of guanine and hypoxanthine with traces of xanthine. Crystals from the mutant sombre consist primarily of xanthine, suggesting there is a disorder of purine metabolism in this mutant. |
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| Keywords: | Guanine hypoxanthine xanthine purine metabolism struvite |
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