Glucose influence on germ tube production inCandida albicans |
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| Authors: | V. Vidotto G. Accattatis Q. Zhang G. Campanini S. Aoki |
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| Affiliation: | (1) Laboratorio Micologia Medica, Istituto Malattie Infettive, Università di Torino, Corso Svizzera 164, 10.149 Torino, Italy;(2) Laboratory of Medical Mycology, Institute of Dermatology, Hua Shan Hospital, Shanghai Medical University, 200040 Shanghai, China;(3) General Research Institute, Nippon Dental University, 1-8 Hamaura-cho, 951 Niigata, Japan |
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| Abstract: | The influence of different glucose concentrations was tested in a minimal synthetic medium onCandida albicans strain. After 18 hours of starvation, germ-tube (GT) production, amount of consumed glucose, oxygen and the pH of the medium were checked every hour from the beginning through the end of the experiment. Optimal GT production was obtained with 1 g/l of glucose. At this concentration the greatest glucose and oxygen consumption were also noted. No pH variations in the medium were observed in all of the glucose concentrations used. At 3 and 5 g/l glucose concentrations a lower GT production were obtained. The Crab-tree effect might interfere with GT production when glucose concentration is higher than 1 g/l. This data may support the hypothesis that GT production is strictly glucose dependent. |
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