| P物质尾核微量注射抑制小鼠胃肌电活动和胃运动 |
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| 引用本文： | 荆浩,林坤伟.P物质尾核微量注射抑制小鼠胃肌电活动和胃运动[J].生理学报,1994,46(1):17-22. |
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| 作者姓名： | 荆浩 林坤伟 |
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| 作者单位： | 大连医学院生理教研室 |
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| 摘 要： | 本文观察了小鼠尾核微量注射Ｐ物质或乙酰胆碱对胃肌电和胃运动的ｍ影响；并初步探讨了两者作用的关系。用双极康铜导线引导胃窦部肌电；用水囊连接压力换能器记录胃窦部运动。上述信息经生物电放大器和载波放大器放大后，由四道记录仪描记曲线，同时输入微机进行采集、贮存和处理。计算出注药前后每分钟胃肌电快波、慢波和胃运动波的频率和总幅度的变化百分数。结果如下：尾核注射ＳＰ或ＡＣｈ胃电快波和胃运动呈明显的抑制效应。用
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| 关 键 词： | 胃肌电活动 胃运动 P物质 尾核 胃 |
INHIBITION OF GASTRIC MYOELECTRIC ACTIVITY AND GASTRIC MOTILITY INDUCED BY MICROINJECTION OF SUBSTANCE P INTO CAUDATE NUCLEUS IN MOUSE |
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| JING HAO AND LIN KUN-WEI.INHIBITION OF GASTRIC MYOELECTRIC ACTIVITY AND GASTRIC MOTILITY INDUCED BY MICROINJECTION OF SUBSTANCE P INTO CAUDATE NUCLEUS IN MOUSE[J].Acta Physiologica Sinica,1994,46(1):17-22. |
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| Authors: | JING HAO AND LIN KUN-WEI |
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| Abstract: | Changes of gastric myoelectric fast wave,slow wave and gastric motility were studied after microinjection of substance P or ACh into caudate nucleus in an attempt to find the interaction between the two substances. Gastric myoelectric activity and motili ty were recorded by a RM-6200 four channel recorder and then delivered to a IBM-PC computer for analysis. After microinjection of SP or ACh into caudate nucleus, the gastric myoelectric fast wave and gastric motility were significantly suppressed, while the slow wave was not siginificantly changed. |
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| Keywords: | gastric myoelectric activity gastric motility substance P acetylcholine caudate nucleus |
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