Influence of comorbidity with depression on interdisciplinary therapy: outcomes in patients with chronic low back pain |
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| Authors: | Haili Wang Carsten Ahrens Winfried Rief Marcus Schiltenwolf |
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| Institution: | (1) Department of Orthopaedic Surgery, University of Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany;(2) Department of Clinical Psychology and Psychotherapy, University of Marburg, Gutenbergstrasse 18, 35032 Marburg, Germany |
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| Abstract: | Introduction Our previous work showed higher tumour necrosis factor (TNF)-α levels in patients with chronic low back pain (cLBP) compared
to healthy controls. However, patients with depression as a comorbidity did not have higher TNF-α levels in comparison to
patients without depression. In this study we investigated the influence of depression on therapy outcomes such as TNF-α serum
levels, pain intensity and back function in patients with cLBP. Our hypothesis was that patients with both cLBP and depression
benefit no less than patients with cLBP alone from the multidisciplinary pain therapy. |
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