Revisiting caveolin trafficking: the end of the caveosome |
| |
Authors: | Parton Robert G Howes Mark T |
| |
Institution: | Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia. R.Parton@imb.uq.edu.au |
| |
Abstract: | In this issue, a study by Hayer et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201003086) provides insights into the trafficking of caveolins, the major membrane proteins of caveolae. As well as providing evidence for ubiquitin-mediated endosomal sorting and degradation of caveolin in multivesicular bodies (MVBs), the new findings question the existence of a unique organelle proposed nine years ago, the caveosome. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|