Bidirectional transcription of a novel chimeric gene mapping to mouse chromosome Yq |
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Authors: | Peter JI Ellis Lydia Ferguson Emily J Clemente Nabeel A Affara |
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Affiliation: | (1) Mammalian Molecular Genetics Group, University of Cambridge Department of Pathology, Tennis Court Rd., CB2 1QP Cambridge, UK |
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Abstract: | Background The male-specific region of the mouse Y chromosome long arm (MSYq) contains three known highly multi-copy X-Y homologous gene families, Ssty1/2, Sly and Asty. Deletions on MSYq lead to teratozoospermia and subfertility or infertility, with a sex ratio skew in the offspring of subfertile MSYqdel males |
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