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Atherosclerosis: a physical-thermodynamic hypothesis for its genesis
Authors:R G Taborsky
Affiliation:1. Department of Pulmonology, Division of Heart & Lungs, University Medical Centre Utrecht, PO Box 85500, Utrecht 3508 GA, The Netherlands;2. Faculty of Health, Medicine and Life Science, Maastricht University, Maastricht, The Netherlands;3. Department of Respiratory Medicine, ILD Center of Excellence, St. Antonius Hospital, Nieuwegein, The Netherlands;4. ILD Care Foundation Research Team, Heideoordlaan 8, Ede 6711NR, The Netherlands;5. Department of Neurology, School of Medicine, Johns Hopkins University, 601 North Caroline Street, Neurology Room 5066B, Baltimore, MD 21287, USA;1. Department of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland;2. Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague 4, Czech Republic;3. Department of Gastroenterology and Hepatology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland;1. School of Science and Engineering, University of Dundee, Dundee, United Kingdom;2. Sustainable Development, De Montfort University Leicester, United Kingdom;3. School of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield, United Kingdom;4. Mechanical Mechatronics Engineering, Afe Babalola University, Ado Ekiti, Nigeria
Abstract:A hypothesis is advanced that atherosclerosis is a result of fundamental changes in the physics of the circulatory system with physiological changes being consequences. Major emphasis is placed on two possible conditions. One is that of aberration of surface tension as expressed in the Gibb's Adsorption isotherm. The other postulates the existence of a natural plasticizer substance and its deficiency in atherosclerotic disease.
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