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A structured ancestral population for the evolution of modern humans
Authors:Harding Rosalind M  McVean Gil
Institution:Biological Anthropology Unit and Statistics Department, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK. rosalind.harding@bioanthropology.oxford.ac.uk
Abstract:The view that modern humans evolved through a bottleneck from a single founding group of archaic Homo is being challenged by new analyses of contemporary genetic variation. A wide range of middle to late Pleistocene ages for gene genealogies and evidence for early population structures point to a diverse and scattered ancestry associated with a metapopulation history of local extinctions, re-colonization and admixture. A different balance of the same processes has shaped chimpanzee diversity.
Keywords:Abbreviations: mtDNA  mitochondrial DNA  Ne  effective population size  NRY  non-recombining part of Y chromosome  RAO  recent African origin  SNP  single nucleotide polymorphism  TMRCA  time to the most recent common ancestor
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