Ras-regulated signaling processes in Saccharomyces cerevisiae. |
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Authors: | J R Broach |
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Affiliation: | Department of Molecular Biology, Princeton University, New Jersey 08544. |
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Abstract: | Molecular genetics has proved quite successful in identifying the components of RAS-mediated signal transduction in the yeast Saccharomyces cerevisiae and in defining the nature of their interactions. Recently, the emphasis has shifted to a biochemical approach as the processes of guanine nucleotide exchange, GTPase stimulation activity and posttranslational modification of Ras proteins have all been reproduced in vitro. |
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