BRAIN-SPECIFIC ANTIGENS IN THE QUAKING MOUSE DURING ONTOGENY |
| |
| Authors: | C. M. Jacque, O. S. Jø rgensen, Nicole A.,Baumann Elisabeth,Bock |
| |
| Affiliation: | Laboratoire de Neurochimie, INSERM U134 Hôpital de la Salpêtriere, 75013 Paris, France;Psychochemistry Institute, University of Copenhagen, Denmark;The Protein Laboratory, University of Copenhagen, Denmark |
| |
| Abstract: | Abstract— By means of crossed Immunoelectrophoresis the concentrations of 7 brain-specific antigens have been investigated during the ontogenic development of normal and Quaking mice. Two proteins, the glial fibrillary acidic protein and the brain-specific membrane protein D5 were found to be strongly increased in mutant brains. The synaptosomal antigen synaptin (Cl), the 14-3-2 protein of neuronal cytoplasm, and the neuronal membrane antigens D1, D2 and D3 were all present at normal levels in mutant brains. |
| |
| Keywords: | |
|
|
