THIAMINE METABOLISM IN NEUROSPORA CRASSA |
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| Authors: | Bruce M Eberhart E L Tatum |
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| Institution: | Department of Biology, Princeton University, Princeton, New Jersey
Rockefeller Institute of Medical Research, New York, New York |
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| Abstract: | Eberhart , Bruce M. (Princeton U., Princeton, New Jersey), and E. L. Tatum . Thiamine metabolism in Neurospora crassa , Amer. Jour. Bot. 48(8): 702–711. Illus. 1961.—Growth adaptation is a regular feature of the vegetative cycle of thi-1 strains of Neurospora crassa but not of thi-2 or thi-3 strains. The adaptive growth of thi-1 strains is paralleled by the production of cocarboxylase and carboxylase levels which are similar to those of wild-type strains. The growth responses of thi-1,2 and thi-1,3 double mutant strains to thiamine indicates that the thi-1 gene is concerned with the utilization (pyrophosphorylation) of thiamine. |
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