Conceptual,methodological and ethical issues in genetic engineering (1989) |
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Authors: | A Falek |
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Institution: | (1) Department of Psychiatry, Emory University, 30306 Atlanta, Georgia, USA;(2) Human and Behavior Genetics Research Laboratory, Georgia Mental Health Institute, 1256 Briarcliff Road, N.E., 30306 Atlanta, Georgia, USA |
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Abstract: | An introduction to the potential of gene therapy to alleviate illness and death particularly for many rare human genetic disorders
and specific forms of cancer is presented. At present, genetic engineering, that is gene therapy to correct some of these
disorders based on new molecular biology procedures is a possibility in the near future especially those with single gene
mendelian inherited transmission. After a short, comprehensive overview about the molecular biology of genetic engineering,
a presentation of many of the ethical issues now under discussion by the international scientific community, world govenmental
agencies and concerned laymen about the complex and sensitive ethical issues is provided. A report about a case history of
investigators in the United States who disregarded current restrictions emphasized the concern of the scientific community
as well as the governmental agencies in maintaining stepwise, careful approach to the introduction of the new, molecular methodologies.
The continued maintenance of many of these restrictions, suggested by some ethicists, even after the threat of uncontrolled
biological disorder as a result of these new procedures was found to be erroneous is discussed and challenged. |
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Keywords: | 1 Human genetic engineering 2 Human gene therapy |
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