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A small molecule that mimics the BB-loop in the Toll interleukin-1 (IL-1) receptor domain of MyD88 attenuates staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice
Authors:Kissner Teri L  Moisan Lionel  Mann Enrique  Alam Shahabuddin  Ruthel Gordon  Ulrich Robert G  Rebek Mitra  Rebek Julius  Saikh Kamal U
Institution:Department of Immunology, Army Medical Research Institute of Infectious Diseases, Frederick, Maryland 21702, USA.
Abstract:
Keywords:Bacterial Toxins  Cytokines Induction  MyD88  Signal Transduction  Toll-like Receptors (TLR)  BB-loop  Inflammation  Staphylococcal Enterotoxin B  Synthetic Mimetics  Toxic Shock
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