阳离子抗菌肽的研究进展

阳离子抗菌肽(Cationic antibacterial peptides)是生物体抵御外源性病原微生物的入侵而产生的一类小分子阳离子多肽，与传统的抗生素相比具有分子量小、抗菌谱广、热稳定性好、抗菌机理独特等优点。本文结合当今阳离子抗菌肽的研究现状和发展前景，从阳离子抗菌肽的理化性质、作用机理及其设计合成等方面进行了综述。

Research advances in cationic antimicrobial peptides

Cationic antimicrobial peptides are a kind of peptides with anti-extrogenous pathogen activities. They are derived from biological defence system. Most peptides share common features such as small size, strong heat steadiness, wide antibacterial spectrum and special antibacterial mechanism, which are different from other general antibiotic. According to the research report, this paper overviewed sorts, antimicrobial mechanism, design and synthesis of cationic antimicrobial peptides.