| 威灵仙多糖对舌鳞癌细胞生长抑制作用的研究 |
| |
| 引用本文： | 李俊妍,钟辉,李德超. 威灵仙多糖对舌鳞癌细胞生长抑制作用的研究[J]. 生物技术通讯, 2011, 22(2): 255-257. DOI: 10.3969/j.issn.1009-0002.2011.02.025 |
| |
| 作者姓名： | 李俊妍 钟辉 李德超 |
| |
| 作者单位： | 1. 佳木斯大学,口腔医学院,黑龙江,佳木斯,154007
2. 军事医学科学院,生物工程研究所,北京,100850 |
| |
| 基金项目： | 教育部留学回国人员科研启动基金(教外司留[2007]24号) |
| |
| 摘 要： | 目的:探讨威灵仙多糖对人舌鳞癌细胞Tca-8113的体外生长抑制作用。方法:提取分离纯化威灵仙多糖,用噻唑蓝(MTT)法测定在不同浓度威灵仙多糖作用下人舌鳞癌细胞Tca-8113的活力,观察药物对癌细胞的生长抑制作用。结果:威灵仙多糖对Tca-8113的生长具有明显的抑制作用,随着威灵仙多糖浓度的增大或作用时间延长,抑制作用逐渐增强,呈一定的剂量和时间依赖关系。结论:在体外实验中,威灵仙多糖对人舌鳞癌细胞Tca-8113具有明显的杀伤和抑制作用,可进一步研究其作为抗肿瘤药物应用于临床的潜力。
|
| 关 键 词： | 威灵仙 多糖 舌鳞癌细胞 生长抑制 |
Polysaccharide from Clematis chinensis Osbeck Inhibited the Growth of Tongue Squamous Cell Carcinoma |
| |
| LI Jun-Yan,ZHONG Hui,LI De-Chao .College of Oral Medicine,Jiamusi University,Jiamusi ,.Beijng Institute of Biotechnology,Beijing ,China. Polysaccharide from Clematis chinensis Osbeck Inhibited the Growth of Tongue Squamous Cell Carcinoma[J]. Letters in Biotechnology, 2011, 22(2): 255-257. DOI: 10.3969/j.issn.1009-0002.2011.02.025 |
| |
| Authors: | LI Jun-Yan ZHONG Hui LI De-Chao .College of Oral Medicine Jiamusi University Jiamusi .Beijng Institute of Biotechnology Beijing China |
| |
| Affiliation: | LI Jun-Yan1,ZHONG Hui2,LI De-Chao1 1.College of Oral Medicine,Jiamusi University,Jiamusi 154007,2.Beijng Institute of Biotechnology,Beijing 100850,China |
| |
| Abstract: | Objective:To study the inhibitory effect of polysaccharides from Clematis chinensis on the human tongue squamous cell carcinoma Tca-8113 cells.Methods:Clematis chinensis polysaccharides were extracted,isolated and purified.The human tongue squamous cell cancer Tca-8113 cells were cultured in vitro with six extracts at different concentrations and incubation times.The growth of cancer cells was analyzed by MTT method.Results:Clematis chinensis polysaccharides significantly inhibited the growth of Tca-8113 ce... |
| |
| Keywords: | Clematis chinensis Osbeck polysaccharide tongue squamous cell carcinoma growth inhibition |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
