Structural correlations in bacterial metabolic networks |
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| Authors: | Sebastian Bernhardsson Philip Gerlee and Ludvig Lizana |
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| Institution: | (1) Center for Models of Life, Niels Bohr Institute, Blegdamsvej 17, DK-2100 Copenhagen ?, Denmark;(2) Wallenberg Laboratory, Institute of Medicine, G?teborg University, G?teborg, Sweden |
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| Abstract: | Background Evolution of metabolism occurs through the acquisition and loss of genes whose products acts as enzymes in metabolic reactions,
and from a presumably simple primordial metabolism the organisms living today have evolved complex and highly variable metabolisms.
We have studied this phenomenon by comparing the metabolic networks of 134 bacterial species with known phylogenetic relationships,
and by studying a neutral model of metabolic network evolution. |
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