Challenges and Opportunities in Radiation-induced Hemorrhagic Cystitis |
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Authors: | Bernadette MM Zwaans Heinz G Nicolai Michael B Chancellor Laura E Lamb |
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Institution: | 1Department of Urology, William Beaumont Hospital, Royal Oak, MI;2Departamento de Urología, Universidad de Chile, Santiago, Chile;3Hospital Clínico San Borja Arriarán, Santiago, Chile;4Oakland University William Beaumont School of Medicine, Royal Oak, MI |
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Abstract: | As diagnosis and treatment of cancer is improving, medical and social issues related to cancer survivorship are becoming more prevalent. Hemorrhagic cystitis (HC), a rare but serious disease that may affect patients after pelvic radiation or systemic chemotherapy, has significant unmet medical needs. Although no definitive treatment is currently available, various interventions are employed for HC. Effects of nonsurgical treatments for HC are of modest success and studies aiming to control radiation-induced bladder symptoms are lacking. In this review, we present current and advanced therapeutic strategies for HC to help cancer survivors deal with long-term urologic health issues. |
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Keywords: | Hemorrhagic cystitis Radiation-induced cystitis Hematuria Cancer survivorship |
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