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A method for concentrating dilute solutions of macromolecules
Authors:H.G. Vartak  M.V. Rele  M. Rao  V.V. Deshpande
Affiliation:Biochemistry Division, National Chemical Laboratory, Poona 411 008, India
Abstract:A simple, inexpensive acrylate polymer which has a capacity to absorb 170 ml of water per g has been developed. It can be used to concentrate dilute solutions of macromolecules such as proteins, nucleic acids, and carbohydrates. The polymer absorbs only low-molecular-weight substances such as glucose, sucrose, and inorganic salts. It can replace the various conventional concentration methods. No special device or electricity is needed for the concentration. The inexpensive polymer, molded in the form of rods, can be very conveniently used as “disposable concentration sticks.”
Keywords:carbohydrate concentration  concentration of macromolecules  dewatering of macromolecules  DNA concentration  polyacrylate gel  protein concentration
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