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RETURN OF THE VESTIBULAR FUNCTION FOLLOWING STREPTOMYCIN TOXEMIA
Authors:John S Chase
Abstract:Of 62 patients given 2 gm. of streptomycin daily for an average of 110 days, 42 had complete loss of vestibular response to caloric stimulation. In the great majority of cases, response returned in varying degrees over a period of two years. The incidence of loss of response was higher among patients who weighed less than 125 pounds than among heavier patients, and it was higher among patients over 45 years of age than among those who were younger. Response returned earlier in the younger patients than in the older.Of 215 patients given 1 gm. of streptomycin for an average of 110 days, 18 had complete loss of vestibular response to stimulation. Sixteen regained response within a year, one in 17 months, and one was lost to study.
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