(1) Department of Human Genetics, Ruhr-University Bochum, Germany;(2) Department of Rheumatology, University Hospital, Magdeburg, Germany;(3) Department of Pediatrics, Carl-Thiem-Hospital, Cottbus, Germany
Abstract:
Background
Rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are complex multifactorial diseases caused by environmental influences and an unknown number of predisposing genes. The present study was undertaken in order to investigate association of polymorphisms in candidate genes with RA and JRA in German subjects.