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Complex genetic predisposition in adult and juvenile rheumatoid arthritis |
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| Authors: | Bianca Miterski Susanne Drynda Gundula B?schow Wolfram Klein Joachim Oppermann J?rn Kekow J?rg Thomas Epplen |
| Affiliation: | (1) Department of Human Genetics, Ruhr-University Bochum, Germany;(2) Department of Rheumatology, University Hospital, Magdeburg, Germany;(3) Department of Pediatrics, Carl-Thiem-Hospital, Cottbus, Germany |
| Abstract: | BackgroundRheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are complex multifactorial diseases caused by environmental influences and an unknown number of predisposing genes. The present study was undertaken in order to investigate association of polymorphisms in candidate genes with RA and JRA in German subjects. |
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