Cellular Mechanisms of Organic Anion Transport in Crustacean Renal Tissue

Decapod Crustacea appear to utilize two overall strategies forexcretion of anionic wasteproducts and xenobiotics. One strategyutilizes a potent renal secretory system; the other utilizesboth modest renal secretion and strong gut secretion (possiblyaided by midgut gland conjugation). In crabs, the level of participationof the renal system in overall excretion is primarily determinedbythe location of an anion pump and a carrier protein. The bladder of Cancer borealis, which strongly secretes themodel organic anion, p-aminohippuric acid (PAH), has a serosalorganic anion pump and a luminal facilitated carrier. The bladderof Cancer trroratus, which reabsorbs PAH from bladder urine,has a luminal organic anion pump and a serosal facilitated carrier.