Effect of controlled substrate feeding on butyric acid production byClostridium tyrobutyricum |
| |
Authors: | Françoise Fayolle Rémy Marchal Daniel Ballerini |
| |
Institution: | (1) Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, 1 et 4 avenue de Bois-Préau, B.P. 311, 92506 Rueil-Malmaison Cédex, France |
| |
Abstract: | Summary Production of butyric acid from wheat flour hydrolysate was studied withClostridium tyrobutyricum. The mode of substrate supply was found a key parameter for fermentation performance as large improvements were obtained by feeding with a non-limiting supply of substrate. With this procedure, increases in product concentration and productivity but also in selectivity and yield for butyrate were obtained. Substrate feeding controlled by the rate of gas production was found preferable to constant rate feeding for reason of convenience and flexibility. In these conditions, a butyrate concentration of 62.8 gl–1 was obtained with a productivity of 1.25 gl–1 h–1, a selectivity of 91.5% and a yield of 0.45 g per g of glucose. |
| |
Keywords: | Fed-batch Fermentation control Wheat flour hydrolysate Fermentation selectivity Butyrate production optimisation |
本文献已被 SpringerLink 等数据库收录! |