An Oocyte-Specific Antigen and Its Possible Role in the Organization of the Ovarian Follicle of the Rat |
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| Authors: | ULRICH MÜ LLER,EDMÉ E URBAN |
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| Affiliation: | Institute of Human Genetics, University of Freiburg i. Br., Albertstraße 11, D-7800 Freiburg, Federal Republic of Germany |
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| Abstract: | An oocyte-specific antigen was detected by an antiserum produced in isogenic Lewis rats. The antigen was sensitive to trypsin treatment. Dissociation-reorganization experiments in vitro , using ovarian cells demonstrated that the antigen is required for the interaction of germ cells and somatic cells. A physiologic role is suggested for this differentiation antigen in follicular morphogenesis and ovarian function. |
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