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Radioprotective activity of aminoarylthiazoles and various mechanisms of action |
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| Authors: | V G Vladimirov O N Chupakhin A P Novikova L G Egorova N I Libikova |
| Abstract: | The amino group is shown to be the reaction center that is primarily responsible for the radioprotective effect of the thiazoles under study. A phenyl residue also contributes to the radioprotective effect. The influence of thiazoles on DNA biosynthesis on radiosensitive tissues plays an important role in the biochemical mechanism of their radioprotective action. |
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