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Microarray-based expression analysis of human osteoblast-like cell response to anodized titanium surface
Authors:Yeonhee Kim  Jun-Hyeog Jang  Young Ku  Jae-Young Koak  Ik-Tae Chang  Hyoun-Ee Kim  Jae-Bong Lee  Seong-Joo Heo
Institution:Department of Prosthodontics, Seoul National University College of Dentistry, Seoul 110-768, Korea.
Abstract:An anodized surface significantly enhanced the adhesion of human osteoblast-like MG-63 cells to titanium. Using cDNA microarray analysis, five genes were differentially expressed while the rest remained unaltered. The results demonstrated that the anodized surface enhances cellular adhesion without significantly affecting the pattern of gene expression.
Keywords:DNA microarray  gene expression  heat shock protein 90 (hsp 90)  oxide layer  titanium
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