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Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies
Authors:H Kawagishi  R Inagaki  T Kanao  T Mizuno  K Shimura  H Ito  T Hagiwara  T Nakamura
Institution:Department of Agricultural Chemistry, Faculty of Agriculture, Shizuoka University, Japan.
Abstract:Some polysaccharide-containing materials were successively extracted from the fruiting bodies of Agaricus blazei with aqueous ammonium oxalate and sodium hydroxide, fractionated, and assayed for antitumor activity. From chemical analyses and n.m.r. data, it was concluded that the most active fraction, FIII-2-b, was comprised of protein and a (1----6)-beta-D-glucan.
Keywords:
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