<Emphasis Type="Italic">Trichosporon inkin</Emphasis> Esophagitis: An Uncommon Disease in a Patient with Pulmonary Cancer |
| |
| Authors: | Danielle Patrícia Cerqueira Macêdo Neiva Tinti de Oliveira Vanessa Karina Alves da Silva Aline Mary de Almeida Farias Reginaldo Gonçalves de Lima Neto Ana Botler Wilheim Patrícia Cariolano de Oliveira Nadyr Pedi Suanni Lemos de Andrade Rejane Pereira Neves |
| |
| Institution: | 1.Departamento de Micologia, Centro de Ciências Biológicas,Universidade Federal de Pernambuco,Recife,Brazil;2.Setor de Endoscopia Digestiva do Laboratório Geral do Hospital,Universitário Oswaldo Cruz,Recife,Brazil |
| |
| Abstract: | Trichosporon species are usually opportunistic pathogens. Here, we present a case of esophagitis caused by T. inkin in a 54-year-old woman with pulmonary cancer and severe neutropenia in whom the susceptibility profile of the isolate against
azoles and polyenes was verified. The patient was diagnosed with esophagitis grade I of Wilcox, presenting scattered whitish
plaques and exudates in upper two-thirds of the esophageal mucosa. Antifungal therapy involving oral fluconazole (150 mg/day
for 14 days) was ineffective. In vitro, the isolate showed no resistance to this azole and sensitivity to amphotericin B.
Since T. inkin is of growing importance as an agent of invasive infections in immunocompromised patients, we stress that the diagnosis of
esophagitis by this species should be followed by an assessment of the therapeutic sensitivity of the strain involved. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
