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鲤鱼线粒体tRNA~(phe)基因结构的特异性
引用本文:米志勇,刘兰香,王钢锋,吴乃虎. 鲤鱼线粒体tRNA~(phe)基因结构的特异性[J]. 分子细胞生物学报, 1996, 0(3)
作者姓名:米志勇  刘兰香  王钢锋  吴乃虎
作者单位:中国科学院发育生物学研究所,中国科学院发育生物学研究所,中国科学院发育生物学研究所,中国科学院发育生物学研究所 北京 100080,北京 100080,北京 100080,北京 100080
摘    要:鲤鱼线粒体tRNA~(phe)基因的核酸序列已被测定。在鲸、人、爪蟾、牛、小鼠、鸡和鲤鱼中对此基因序列比较发现在D茎存在一个奇怪的保守结构,然而D茎在其余种类的已经测定的脊椎动物线粒体tRNA基因和细胞质tRNA基因中是极不保守的。这一保守结构包含有13bp碱基,我们将此保守区前7个碱基与真核生物RNA PolⅢ识别的A区相比较,发现在此不同物种的两种序列存在部分的同源性。考虑到tRNA~(phe)基因在线粒体基因组上位于置换环区和线粒体rRNA基因编码区之间这一特殊区域内,我们推测这一奇怪的保守结构可能存在其它更为有意义的功能。

关 键 词:鲤鱼  线粒体  tRNA~(phe)基因

A NOVEL CONSERVATIVE STRUCTURE FOUND IN THE CARP MITOCHONDRIAL tRNA~(phe) GENE
MI Zhi Yong LIU Lan Xiang WANG Gang Feng WU Nai Hu. A NOVEL CONSERVATIVE STRUCTURE FOUND IN THE CARP MITOCHONDRIAL tRNA~(phe) GENE[J]. Journal of Molecular Cell Biology, 1996, 0(3)
Authors:MI Zhi Yong LIU Lan Xiang WANG Gang Feng WU Nai Hu
Abstract:A nucleotide sequence for the tRNAphe gene of Carp mitochondria was determined. Sequence data comparisons made among the whale, human, Xenopus laevis, bovine, mouse, chicken and carp, showed that a novel conservative structure was found in the D. stem (dihydrouridine stem), which was known had variant nucleotides in any other vertebrate mitochondrial tRNA and cytoplasmic tRNA genes. This conservative structures contains 13 bp. When we com-pared the front 7 bp of the conservative structure with the eukaryotic RNA Pol n recognitive A domain, we found these two kinds of different species had partly ho-mologue. As the mitochondrial tRNAphe gene is located between the displacement loop and mitochondrial rRNA gene, we inferred that the novel conservative structure might have some extra interesting functions.
Keywords:Carp mitochondria. tRNA~(phe) gene.  
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