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An electron-microscopic stereological study of the compensatory hypertrophy of the rat adrenal zona fasciculata after unilateral adrenalectomy |
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| Authors: | Rebuffat Piera Robba Claudia Belloni Anna S. Mazzocchi Giuseppina Vassanelli Paolo Nussdorfer Gastone G. |
| Affiliation: | (1) Department of Anatomy, University of Padua, Padua, Italy;(2) Department of Experimental Surgery, University of Padua, Padua, Italy;(3) Istituto di Anatomia Umana Normale, Via Gabelli 65, 35100 Padova, Italy |
| Abstract: | Summary The ultrastructural changes associated with the compensatory hypertrophy of the zona fasciculata cells on monoadrenalectomized rats were investigated by stereological techniques. It was found that these subcellular changes display a different pattern from those underlying the ACTH-induced adrenocortical cell growth in the intact rats. This result supports the view that compensatory adrenal hypertrophy does not involve activation of the hypothalamo-hypophyseal-adrenal axis. |
| Keywords: | Monoadrenalectomy Compensatory adrenal growth Zona fasciculata Rat Stereology |
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