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The synthesis of a radioactive cytokinin with high specific activity
Authors:Michael R. Sussman  Richard Firn
Affiliation:MSU/AEC Plant Research Laboratory and Department of Botany and Plant Pathology, Michigan State University, East Lansing, Michigan, 48824, U.S.A.
Abstract:6-benzylaminopurine-[p-1H-benzyl] at a specific activity of 10 Ci/mmol was synthesized by reacting p-bromo-6-benzylaminopurine with carrier-free tritium gas in the presence of 10% Pd/C. A radiochemical purity of 97% was obtained by a one-step purification of the tritiated reaction product using cellulose TLC. This simple procedure yields the highly active cytokinin, 6-benzylaminopurine, with tritium at near maximum specific activity in a known, stable position.
Keywords:Tritiated benzyladenine  high specific radioactivity cytokinin  volatile purine tritium  palladium catalyzed dehalogenation.
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