Effects of substituents in the A-ring on the physiological activity of flavones |
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Authors: | Göran Stenlid |
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Institution: | Department of Plant Physiology, Agricultural College of Sweden, S-750 07 Uppsala 7, Sweden |
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Abstract: | The flavonoids quercetagetin, gossypetin and scutellarein 7-glucoside which have o-dihydroxyl groups in the A ring inhibit indole-3-acetic acid oxidase. Since scutellarein 7-glucoside has no such grouping in the B-ring it is clear that it is the hydroxyls in the A-ring that cause the inhibition. The presence of o-dihydroxyls in the A-ring also decreases the inhibitory effect upon ATP formation in mitochondria. |
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Keywords: | Flavones scutellarein quercetagetin gossypetin indole-3-acetic acid oxidase ATP formation |
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