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Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1
Authors:Daniel T Utzschneider  Arnaud Delpoux  Dominik Wieland  Xin Huang  Chen-Yen Lai  Maike Hofmann  Robert Thimme  Stephen M Hedrick
Institution:1. Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA;2. Cellular and Molecular Medicine, UC San Diego, La Jolla, CA 92093, USA;3. Department of Medicine II, University Hospital Freiburg, 79106 Freiburg, Germany
Abstract:
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  • Keywords:immune memory  homeostatic proliferation  self-renewal  quiescence  cell survival  T cells  FOXO  TCF1/TCF7  chronic infection  LCMV
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