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Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current
Authors:Fang Hu  Jingheng Zhou  Yanxin Lu  Lizhao Guan  Ning-Ning Wei  Yi-Quan Tang  KeWei Wang
Affiliation:1. Qingdao University School of Pharmacy, Qingdao 266021, China;2. Department of Molecular and Cellular Pharmacology, Peking University School of Pharmaceutical Sciences, Beijing 100191, China;3. Institute of Innovative Drugs, Qingdao University School of Pharmacy, Qingdao 266071, China
Abstract:
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  • Keywords:Hsp70  Kv4  KChIP4a  seizures  epilepsy  kainic acid  hyperexcitability  A-type current  status epilepticus  spontaneous recurrent seizures
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