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Cas4 Facilitates PAM-Compatible Spacer Selection during CRISPR Adaptation
Authors:Sebastian N. Kieper  Cristóbal Almendros  Juliane Behler  Rebecca E. McKenzie  Franklin L. Nobrega  Anna C. Haagsma  Jochem N.A. Vink  Wolfgang R. Hess  Stan J.J. Brouns
Affiliation:1. Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands;2. Genetics and Experimental Bioinformatics, Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany;3. Freiburg Institute for Advanced Studies, University of Freiburg, Albertstr. 19, 79104 Freiburg, Germany;4. Laboratory of Microbiology, Wageningen University, Stippeneng 4, 6708 WE Wageningen, the Netherlands
Abstract:
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  • Keywords:CRISPR adaptation  Cas4  spacer acquisition  type I-D CRISPR-Cas system
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