Hyoscyamine N-oxide in Atropa belladonna |
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Authors: | J.David Phillipson S.S. Handa |
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Affiliation: | Department of Pharmacognosy, The School of Pharmacy, University of London, 29-39, Brunswick Square, London WC1N 1AX, England |
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Abstract: | Separated organs of Atropa belladonna have been examined for their total alkaloid, hyoscyamine and hyoscyamine N-oxide contents during ontogenesis. Marked fluctuations in N-oxide content were observed, the highest being found in the ripe fruit. [G-3H]-atropine was fed to A. belladonna fruits and radioactively labelled hyoscyamine N-oxide isolated. |
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Keywords: | Solanaceae hyoscyamine ontogenesis |
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