NALL-1, an acute lymphoblastic leukemia cell line with peroxidase activity |
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Authors: | J Yourno W A Samsonoff A Willey P Burkhart F Lizzi A Tartaglia |
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Abstract: | All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in greater than 80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell. |
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