Iodine, carbohydrate and protein metabolism in rats with cobalt deficiency]

Experiments on male rats maintained at the diet with a low amount of cobalt have revealed a decrease in values of iodine indices in organs and tissues except for the liver tissues where a sharp increase in the inorganic iodine concentration as well as disturbances of the protein and carbohydrate metabolism were observed. Mathematical analysis has shown a high correlation of changes in the carbohydrate and protein metabolism and concentration of protein-bound iodine in blood. It has permitted a conclusion on an indirect effect of the cobalt deficiency on the metabolism processes as a result of changes in the concentration of protein-bound iodine in blood and tissues.