Relationship between central cholinergic and GABAergic neurotransmitters activity in the steroid treated rat |
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Authors: | P C Das C D Dey K Pharikal S Dasgupta |
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Affiliation: | Department of Physiology, Calcutta University, College of Sciences and Technology, India. |
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Abstract: | Contraceptive steroid treatment to female rat alters the concentration of acetylcholine and gamma-aminobutyric acid, though not uniformly in most of the brain areas, i.e. in cerebellum, medulla oblongata-pons, hypothalamus, striatum-hippocampus, midbrain-thalamus-subthalamus, and cortex. Both neutrotransmitters vary conjointly in the hypothalamus and striatum-hippocampus after combined steroid treatment. This may indicate a concerted effect on the modulation of gonadotrophin release. |
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