Photochemically induced transformation of adrenochrome to adrenochrome-melanin |
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Authors: | K Polewiski D Slawinska |
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Institution: | Department of Physics, Agricultural University, Poznan, Poland. |
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Abstract: | The photochemical decomposition of adrenochrome in aqueous and deuterated solutions by visible light was investigated. From the spectroscopic study the disappearance constant k = 4.8 x 10(-5) s-1 as well as quenching constant kq = 2.5 x 10(-1) s M-1] and isotope effect kD/kH = 2 for singlet oxygen mechanism have been calculated. A possible chemical mechanism for the observed transformation of adrenochrome to the melanin polymer is discussed including the formation of the reactive intermediate species like cytotoxic quinones. |
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