Up-regulation of CatSper genes family by selenium |
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| Authors: | Shabnam Mohammadi Mansoureh Movahedin Seyed Javad Mowla |
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| Affiliation: | (1) Department of Anatomy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran;(2) Department of Genetics, Faculty of Basic Sciences, Tarbiat Modares University, Tehran, Iran |
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| Abstract: | Background CatSper1-4 are a unique family of sperm cation channels, which are exclusively expressed in the testis and play an important role in sperm motility and male fertility. Despite their vital role in male fertility, almost nothing is known about the factors regulating their expression. Here, we investigated the effects of selenium (Se) on the expression of CatSper genes and sperm parameters in aging versus young male mice. |
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