A glycosylated recombinant human granulocyte colony stimulating factor produced in a novel protein production system (AVI-014) in healthy subjects: a first-in human, single dose, controlled study |
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| Authors: | Roslyn Varki Ed Pequignot Mark C Leavitt Andres Ferber Walter K Kraft |
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| Affiliation: | (1) Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 South 10th Street, 1170 Main Building, Philadelphia, PA 19107, USA;(2) Synageva Biopharma, 111 Riverbend Road, Athens, GA 30605, USA;(3) Cancer Institute of New Jersey at Cooper University Hospital, Camden, NJ 08103, USA |
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| Abstract: | Background AVI-014 is an egg white-derived, recombinant, human granulocyte colony-stimulating factor (G-CSF). This healthy volunteer study is the first human investigation of AVI-014. |
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