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Hemolytic toxin produced by Porphyromonas gingivalis
Authors:Masakazu Hoshi  Iwao Kato  Nobuichi Goto  Kohji Hasegawa
Institution:Department of Periodontics, Showa University Dental School, 2-1-1 Kitasenzoku, Ohta-ku, Tokyo 145, Japan; Department of Oral Microbiology, Showa University Dental School, 2-1-1 Kitasenzoku, Ohta-ku, Tokyo 145, Japan
Abstract:Abstract Porphyromonas gingivalis no. 381 and ATCC 33277 produced an extracellular hemolytic toxin which was heat-labile, trypsin-sensitive, and lytic to human, horse, sheep and rabbit erythrocytes. The hemolytic toxin is a 'hot-cold', thiol-independent toxin. The production of the hemolytic toxin was greatly enhanced by addition of hemoglobin to the culture medium.
Keywords:Hemolytic toxin  Hemolysis              Porhyromonas gingivalis
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